Mechanical Problem

Estimating mechancial properties of muscle from microstructure

stress distribution in REV for different setups

Solving the inverse problem gives us estimates of the skeletal muscle’s microstructure. We can use these estimates to investigate how changes in the microstructure affects the ability of the muscle to transmit force. Changes in the microstructure lead to changes in the mechanical properties of muscle and these mechanical properties influence how well force is transmitted through the muscle. By creating micro-mechanical models of the microstructure, we can investigate how these effective properties are influenced by changes in the microstructure, not unsimilar to what we did with diffusion in the forward problem.

Coming Soon!


Cover Photo: dMRI signal for simplified model of muscle (more info)
© 2019. Noel Naughton – All rights reserved.

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